Horse chestnut (Aesculus hippocastanum L.) is a plant well spread in temperate areas of Europe and Asia. Extracts from seeds contain starch, proteins, triterpene saponines (aescin, also being the common standardization), fatty oils and flavonols glycosides.

Main health activities deriving from horse chestnut extracts are local anti-inflammatory, anti-oedematous and venotonic functions that are particularly indicated in cases of Chronic Venous Insufficiency but also for resolving symptoms from minor traumatic events.  Aescin influences microcirculation by normalizing vascular permeability, increasing capillaries resistance thus reducing liquid leakage.  Subjective symptoms such as pruritus, pain and feeling of heaviness in the legs are also improved.