The active principles of Vitis vinifera L. leaves make them an excellent tonic for veins and capillaries, which allows for a better blood circulation and for a better irrigation of the different tissues. Red vine is rich in choline, inositol, and vitamin C. It contains proanthocyanidins, compounds that have been shown to reduce the risk of cardiovascular disease. These substances also act as antioxidants, protecting blood vessels from free radicals, and are effective antihistamine and anti-inflammatory compounds.